Meanwhile, Penix has the Huskies favored by 20.5 points, per the Week 4 college football lines, after he tossed for 375 yards and four touchdowns in the first half of his last game. The Trojans are massive 34.5-point favorites in the SportsLine consensus Week 4 college football odds, marking the fourth straight game Williams and co.

ET, while at that same time, Michael Penix Jr. 5 USC will visit Arizona State at 10:30 p.m. The two biggest Heisman favorites will get chances to add to their resumes in separate late-night games on Saturday.